Last updated 5 months ago
Biotech innovation is controlled by centralized institutions, restricting participation, slowing early validation, and preventing transparent, global scientific collaboration.
A Cardano-based decentralized biotech collaboration network enabling global scientific contribution, transparent validation, and on-chain attribution of participation.
Please provide your proposal title
AXC:Decentralized Biotech Collaboration Network on Cardano
Enter the amount of funding you are requesting in ADA
165000
Please specify how many months you expect your project to last
6
Please indicate if your proposal has been auto-translated
No
Original Language
en
What is the problem you want to solve?
Biotech innovation is controlled by centralized institutions, restricting participation, slowing early validation, and preventing transparent, global scientific collaboration.
Supporting links
Does your project have any dependencies on other organizations, technical or otherwise?
Yes
Describe any dependencies or write 'No dependencies'
Engaging Cardano builders exploring decentralized identity, governance, and coordination tooling for scientific collaboration.
Will your project's outputs be fully open source?
Yes
Please provide details on the intellectual property (IP) status of your project outputs, including whether they will be released as open source or retained under another licence.
Governance patterns, workflow documentation, and the collaboration playbook will be open-source. Prototype components will use a permissive license when feasible.
Please choose the most relevant theme and tag related to the outcomes of your proposal
Healthcare
Describe what makes your idea innovative compared to what has been previously launched in the market (whether by you or others).
No Catalyst project to date has adapted the Catalyst governance stack for scientific collaboration. While Cardano has funded tools for identity, metadata, and governance, none have attempted to reuse these components to create a decentralized scientific workflow layer that supports research contribution, transparent peer evaluation, and on-chain attestations.
This project is innovative because it introduces an entirely new application category to Cardano: structured decentralized science (DeSci). Instead of building financial primitives, we are building coordination primitives for early-stage scientific research—submission, review, validation, and governance—designed to operate transparently and globally for the first time on Cardano.
The concept reframes Catalyst not as a funding mechanism but as a model for decentralized, community-driven scientific validation, establishing Cardano as a leader in research coordination.
Describe what your prototype or MVP will demonstrate, and where it can be accessed.
The MVP will demonstrate how scientific collaboration can occur in a decentralized, transparent, and globally accessible way using Cardano tools. It will allow contributors to:
The prototype will be deployed publicly on a Vercel-hosted web portal, integrated with Cardano testnet, and accessible to any community member. All documentation, governance workflows, and the “Decentralized Biotech Collaboration Playbook” will be available on GitHub.
Describe realistic measures of success, ideally with on-chain metrics.
On-chain Metrics
Off-chain Metrics
Qualitative Metrics
Success is defined by a demonstrable, working decentralized coordination model for scientific research, with real contributors performing testnet-verifiable actions.
Please describe your proposed solution and how it addresses the problem
Biotech innovation affects billions of people, yet the early stages of scientific collaboration remain centralized, expensive, and inaccessible. Independent researchers, smaller institutions, and global contributors struggle to participate because the path from early ideas to validated insights is shaped by a small number of dominant institutions. These gatekeepers control funding, validation, and access, in part due to the extremely high cost of drug development and the dependency on complex intellectual property pathways that reinforce centralization.
As a result, promising ideas often fail to progress, interdisciplinary contributors are undervalued, and scientific validation lacks transparency. Existing collaboration systems are fragmented, opaque, and not designed for open participation.
Our solution creates a decentralized biotech collaboration network built on Cardano, enabling global contributors to coordinate around early-stage scientific ideas through transparent workflows, on-chain attribution, and decentralized governance. The platform supports structured submissions of hypotheses, protocols, datasets, analyses, and reviews, all tied to contributor identities and verifiable participation records.
A key component of this project is evaluating how elements of the Project Catalyst governance and coordination stack can be adapted for scientific collaboration. Catalyst has already demonstrated large-scale decentralized decision making across thousands of participants. By reusing identity mechanisms, metadata standards, governance cycles, and workflow patterns, we reduce development cost, increase feasibility, and strengthen alignment with Cardano’s established governance ecosystem.
The MVP will include a contributor identity layer, a scientific submission and review engine, a governance model inspired by Catalyst, on-chain attestations for validated interactions, and a contribution-based reputation system. A public collaboration portal will demonstrate decentralized scientific workflows and allow participation on testnet.
This initiative is unique because it brings decentralized scientific coordination to Cardano while directly addressing the structural bottlenecks of traditional biotech: high development costs, reliance on restrictive IP frameworks, and centralized control over early-stage scientific decision making. It expands Cardano’s real-world utility and positions the ecosystem as a foundation for transparent, global scientific collaboration.
The MVP will include:
This initiative fills a major gap in **decentralized science (DeSci) **by providing a structured layer for early collaboration and transparent scientific validation—building a new avenue for scientific innovation on Cardano.
Please define the positive impact your project will have on the wider Cardano community
This project significantly expands Cardano’s real-world utility by extending Catalyst’s governance capabilities to scientific collaboration. The result: Cardano becomes the first blockchain to support decentralized, structured scientific coordination at scale and provides a direct ROI on the significant investment already made in Catalyst’s infrastructure.
A key benefit of this initiative is its ability to generate sustained on-chain activity for Cardano. Every scientific submission, review, endorsement, validation event, governance vote, and contributor interaction will produce associated on-chain attestations or metadata entries. Researchers submit work that anchors attribution records on-chain; reviewers issue attestations tied to their validation actions; contributors participate in governance cycles modeled after Catalyst, creating measurable voting transactions; and reputation scoring updates are triggered by on-chain events. This creates a continuous flow of verifiable, decentralized interactions that strengthen Cardano’s role as a coordination layer for scientific knowledge, ensuring consistent testnet and eventual mainnet transaction volume tied directly to meaningful real-world collaboration.
Ecosystem Impact
Impact Measurement
Quantitative Metrics
Qualitative Metrics
Output Sharing
All workflows, governance models, metadata schemas, and the Decentralized Biotech Collaboration Playbook will be publicly accessible on GitHub. We will share updates through Town Halls, developer channels, and decentralized science communities.
What is your capability to deliver your project with high levels of trust and accountability? How do you intend to validate if your approach is feasible?
The project is feasible within the proposed timeline due to the team's experience in scientific workflow design, decentralized governance frameworks, and Cardano engineering. The milestones progress in a clear sequence from conceptual design to a functional MVP and community validation.
Feasibility is strengthened by the planned reuse of components from the Project Catalyst governance stack. Identity models, metadata structures, voting cycles, and coordination patterns already developed in the ecosystem provide a proven foundation and reduce implementation complexity. The team is in communication with relevant contributors in the Cardano ecosystem to ensure alignment and to identify where Catalyst components can be integrated effectively.
The project team understands the complexity of the full long-term vision and has defined a focused MVP scope that is technically achievable, avoids unnecessary regulatory overhead, and stays within the team's existing capabilities. This allows the MVP to concentrate on workflows, on-chain verification, and governance interactions that can be delivered reliably within Fund 15 constraints.
All milestone outputs are independently verifiable through a live portal, testnet transactions, and public documentation, which ensures transparency and accountability.
Milestone Title
Research & Design
Milestone Outputs
Output (A): Research & Design Package
(A1) Submission workflow defined
(A2) Contributor role taxonomy documented
(A3) Governance cycle modeled on Catalyst
(A4) Catalyst reuse assessment completed
(A5) Feasibility review completed
(A6) Package prepared for portal integration
Output (B): Network Charter Draft
(B1) Participation rules defined
(B2) Governance aligned
(B3) Charter formatted and ready for publication
Acceptance Criteria
For Output (A):
(A-AC1) Workflow clearly defined and validated
(A-AC2) Role taxonomy mapped to workflows
(A-AC3) Governance cycle based on Catalyst
(A-AC4) Catalyst component analysis complete
(A-AC5) Feasibility review documented
(A-AC6) Package prepared for MVP integration
For Output (B):
(B-AC1) Rules and expectations documented
(B-AC2) Governance aligned with workflows
(B-AC3) Charter finalized and formatted
Evidence of Completion
(A-E1) The finalized Research & Design Package, including workflows, governance cycles, and Catalyst reuse analysis, will be uploaded to a dedicated GitHub repository with complete version history.
(B-E1) A fully formatted PDF of the Draft Network Charter, aligned with workflows and governance cycles, will be published in the project’s GitHub repository with timestamped commit history.
Delivery Month
1
Cost
25000
Progress
20 %
Milestone Title
Contributor & Research Portal MVP
Milestone Outputs
Output (A): MVP Portal Deployment
(A1) Public portal deployed
(A2) Contributor onboarding implemented
(A3) Researcher onboarding implemented
(A4) Reviewer onboarding implemented
(A5) Documentation library integrated
(A6) Contributor dashboards enabled
Output (B): Submission & Review Workflows
(B1) Submission template deployed
(B2) Review workflow functional
(B3) Validation steps integrated
(B4) Reviewer UI implemented
(B5) Submission tracking active
Acceptance Criteria
For Output (A):
(A-AC1) Portal publicly accessible
(A-AC2) At least 20 contributors onboarded
(A-AC3) At least 5 researchers onboarded
(A-AC4) At least 3 reviewers onboarded
(A-AC5) Documentation fully browsable
(A-AC6) Dashboards update correctly
For Output (B):
(B-AC1) End-to-end submissions functional
(B-AC2) Review workflow complete
(B-AC3) Validation workflow enabled
(B-AC4) Reviewer UI fully operational
(B-AC5) Internal testing passed
Evidence of Completion
(A-E1) The publicly accessible portal URL, onboarding logs, and screenshots showing functional dashboards and documentation will be uploaded to GitHub for community verification.
(B-E1) Screenshots and a recorded video walkthrough demonstrating submission, review, and validation workflows will be posted in the GitHub documentation folder with commit history.
Delivery Month
3
Cost
40000
Progress
50 %
Milestone Title
On-Chain Attestation & Governance Prototype
Milestone Outputs
Output (A): On-Chain Attestation Layer
(A1) Attestation scripts deployed
(A2) Metadata schema finalized
(A3) Portal integration complete
(A4) Identity-linked attestations enabled
Output (B): Governance Prototype
(B1) Proposal submission live
(B2) Voting cycle modeled after Catalyst
(B3) Governance dashboard implemented
(B4) Governance simulation logic added
Output (C): Reputation System
(C1) Scoring logic defined
(C2) Contribution weighting mapped
(C3) Scores auto-update from attestations
Acceptance Criteria
For Output (A):
(A-AC1) At least 30 attestations recorded
(A-AC2) Metadata schema validated
(A-AC3) Portal displays attestations
(A-AC4) Identity linkage verified
For Output (B):
(B-AC1) At least 3 governance test votes
(B-AC2) Catalyst-style logic functional
(B-AC3) Governance UI interactive
(B-AC4) On-chain decision records visible
For Output (C):
(C-AC1) Scoring reflects contribution types
(C-AC2) Automatically updates on attestations
(C-AC3) Shown in contributor dashboards
Evidence of Completion
(A-E1) A complete list of testnet transaction hashes, contract endpoints, and metadata entries will be published in GitHub to verify successful attestation functionality.
(B-E1) Governance simulation logs and screenshots, including vote submissions and final results, will be committed to GitHub for public review and verification.
(C-E1) A video demonstration and screenshots showing dynamic reputation score updates triggered by on-chain events will be uploaded to GitHub and publicly linked.
Delivery Month
5
Cost
70000
Progress
80 %
Milestone Title
Community Validation & Playbook Release
Milestone Outputs
Output (A): Community Validation Cycle
(A1) 30+ testers participate
(A2) All workflows tested end-to-end
(A3) Governance simulation completed
(A4) Feedback collected and categorized
Output (B): Decentralized Biotech Collaboration Playbook
(B1) Playbook drafted
(B2) Scientific workflows documented
(B3) Governance, metadata, and attestation models included
(B4) Playbook published publicly
Acceptance Criteria
For Output (A):
(A-AC1) 30+ community participants
(A-AC2) All workflows verified
(A-AC3) Governance cycle completed
(A-AC4) Feedback documented
For Output (B):
(B-AC1) Playbook
(B-AC2) Includes all workflow components
(B-AC3) Publicly published
Evidence of Completion
(A-E1) Full testing logs, participant summaries, and categorized feedback documents will be released in GitHub to demonstrate the successful execution of the validation cycle.
(B-E1) The finalized Playbook PDF, including governance, workflow, and attestation models, will be published in GitHub with version control and public access.
Delivery Month
6
Cost
30000
Progress
100 %
Please provide a cost breakdown of the proposed work and resources
The total requested budget is ₳165,000, allocated across four milestones in a 6-month development cycle. Each milestone includes clearly defined tasks that directly support the delivery of a functional decentralized biotech collaboration MVP on Cardano.
Milestone 1 — Research & Design (₳25,000 | 20%)
Tasks & Costs:
Justification:
This milestone requires specialized scientific workflow design, governance modeling, and Catalyst-pattern analysis—high-skill, foundational work that sets the structure for the entire MVP.
Milestone 2 — Portal MVP (₳40,000 | 30%)
Tasks & Costs:
Justification:
A multi-role collaboration portal requires UX, full-stack development, workflow integration, and intuitive UI design. This milestone produces the public-access MVP for contributor engagement.
Milestone 3 — On-Chain Attestation & Governance Prototype (₳70,000 | 42%)
Tasks & Costs:
Justification:
This is the most technically complex milestone. It includes Aiken/Plutus Lite smart contracts, governance mechanics, metadata standards, scoring models, and full testnet simulation—high-value engineering work central to Cardano utility.
Milestone 4 — Community Validation & Playbook Release (₳30,000 | 18%)
Tasks & Costs:
Justification:
This milestone completes the full system validation, produces a reusable playbook for DeSci teams, and ensures public transparency through structured documentation.
Budget Summary
Milestone ADA %
Milestone 1 — Research & Design ₳25,000 20%
Milestone 2 — Portal MVP ₳40,000 30%
Milestone 3 — On-Chain Prototype ₳70,000 42%
Milestone 4 — Validation & Playbook ₳30,000 18%
Total ₳165,000 100%
How does the cost of the project represent value for the Cardano ecosystem?
This project provides strong value for the Cardano ecosystem by extending the Catalyst governance stack—already one of Cardano’s largest technical investments—into a new high-impact domain: scientific collaboration and decentralized research validation.
Key Value Drivers
Direct ROI on Catalyst infrastructure:
The project evaluates and reuses Catalyst identity, governance, and metadata components, reducing engineering cost while strengthening ecosystem coherence.
New high-value utility for Cardano:
Cardano becomes the first blockchain to support structured scientific contribution, peer review, and transparent validation workflows—an entirely new DeSci category.
On-chain transaction generation:
Attestations, governance votes, identity interactions, and reputation scoring all produce verifiable on-chain activity.
Reusable tooling:
Metadata schemas, governance patterns, workflow templates, and the collaboration playbook can be adopted by future scientific communities, DeSci teams, and Cardano builders.
Lean and efficient budget:
A six-month, ₳165k MVP delivers a functioning portal, on-chain attestation system, governance prototype, and community-validated collaboration framework—significant technical and domain scope for a modest allocation.
Long-term ecosystem benefit:
The project positions Cardano as a platform not only for finance but for decentralized knowledge creation, attracting foundations, researchers, and scientific institutions seeking transparent collaboration infrastructure.
Overall, the budget is proportional to the technical and scientific complexity involved, the deliverables are verifiable, and the outcome significantly enhances Cardano’s role in decentralized coordination.
I confirm that evidence of prior research, whitepaper, design, or proof-of-concept is provided.
Yes
I confirm that the proposal includes ecosystem research and uses the findings to either (a) justify its uniqueness over existing solutions or (b) demonstrate the value of its novel approach.
Yes
I confirm that the proposal demonstrates technical capability via verifiable in-house talent or a confirmed development partner (GitHub, LinkedIn, portfolio, etc.)
Yes
I confirm that the proposer and all team members are in good standing with prior Catalyst projects.
Yes
I confirm that the proposal clearly defines the problem and the value of the on-chain utility.
Yes
I confirm that the primary goal of the proposal is a working prototype deployed on at least a Cardano testnet.
Yes
I confirm that the proposal outlines a credible and clear technical plan and architecture.
Yes
I confirm that the budget and timeline (≤ 12 months) are realistic for the proposed work.
Yes
I confirm that the proposal includes a community engagement and feedback plan to amplify prototype adoption with the Cardano ecosystem.
Yes
I confirm that the budget is for future development only; excludes retroactive funding, incentives, giveaways, re-granting, or sub-treasuries.
Yes
I Agree
Yes
Avi Kamelhar — Project Lead
LinkedIn: www.linkedin.com/in/avi-kamelhar-82b1272
Avi brings over 20 years of leadership across biotech operations, clinical research systems, and scientific workflow design. He has deep experience evaluating early-stage scientific concepts, structuring research programs, coordinating multidisciplinary teams, and building systems that support transparent clinical and scientific collaboration. As Project Lead, Avi oversees domain architecture, workflow modeling, contributor coordination, and ensures all platform components reflect real-world scientific needs and collaboration patterns.
Henry Hazan — Tech Lead
LinkedIn: linkedin.com/in/henry-h-77b94116
GitHub: github.com/henry-hz[insert]
Henry is an engineer specializing in Aiken, Plutus Lite, decentralized governance patterns, and metadata standards. He has contributed to multiple blockchain development initiatives and brings strong experience designing secure on-chain coordination tools. As Tech Lead, Henry guides the technical architecture, smart contract implementation, metadata schema development, and the integration of scientific workflows with Cardano testnet.
Dr. Judd Boczko — Scientific Workflow Contributor
LinkedIn: linkedin.com/in/judd-boczko-931b5933
Dr. Boczko is a Medical/scientific advisor with extensive experience reviewing early-stage research, evaluating data packages, and advising founders and investors on scientific and technical feasibility. His expertise spans biological discovery, experimental validation, and translational research assessment. As Scientific Workflow Contributor, Dr. Boczko helps shape scientific submission templates, peer-review structures, and validation logic to ensure workflows align with rigorous scientific standards.
Yoav- Ben-Shalom — Portal & UX Contributor
LinkedIn: linkedin.com/in/yb1189273
Yoav is an experienced product and UX designer with a strong background in building intuitive, human-centered digital platforms. His work spans complex SaaS interfaces, workflow tools, and user dashboards designed for clarity, accessibility, and efficient user interaction. He specializes in transforming abstract system requirements into clear, user-friendly experiences that support real-world collaboration and decision-making.
As Portal & UX Contributor, Yoav leads the design of the contributor onboarding flows, submission and review interfaces, and collaboration dashboards. He ensures that researchers, reviewers, and community participants can navigate the decentralized scientific workflow seamlessly and that the MVP portal reflects best practices in usability, structure, and user engagement.
Governance Design Contributor (TBD)
This contributor will specialize in decentralized governance and decision-making frameworks, helping adapt Project Catalyst governance patterns—including roles, voting cycles, prioritization mechanics, and proposal evaluation workflows—to scientific collaboration. They will develop governance documentation, contributor role definitions, and cycles for scientific prioritization.